Publications

Articles

Roberts, G. Bahnson. HT. Du Toit, G. O’Rourk, C. Sever, M, Brittain, E. Plaut, M. Lack, G. (2023). Defining the window of opportunity and the target populations to prevent peanut allergy. J Allergy Clin Immunol., 151 (5), 1329-1336. http://dx.doi.org/10.1016/j.jaci.2022.09.042, PMID: 36521802, PMCID: PMC10689252

Suprun M, Bahnson HT, Du Toit G, Lack G, Suarez-Farinas M, Sampson HA. (2023). In children with eczema, expansion of epitope-specific IgE is associated with peanut allergy at 5 years of age.. Allergy, 78 (2), 586-589.. http://dx.doi.org/10.1111/all.15572, PMID: 36321870

Berti A, Hillion S, Konig MF, Casal Moura M, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D. (2023). Autoreactive plasmablasts after B cell depletion with rituximab and relapses in ANCA-associated vasculitis. Arthritis Rheumatol, 75 (5), 736-747. http://dx.doi.org/10.1002/art.42388, PMID: 36281741, PMCID: PMC10280646

Baloh CH, Kanchan K, Shankar G, Nepom GT, Mathias RA, Perry JA. (2023). Omics-Oriented Research illustrated with the LEAP Study and the OASIS Bioinformatics Tool.. The Journal of Allergy and Clinical Immunology, 151 (2), 416-419. http://dx.doi.org/10.1016/j.jaci.2022.12.003, PMID: 36521801

Odler B, Riedl R, Gauckler P, Shin JI, Leierer J, Merkel PA, St Clair W, Fervenza F, Geetha D, Monach P, Jayne D, Smith RM, Rosenkranz A, Specks U, Stone JH, Kronbichler A; RAVE−ITN Research Group. (2023). Risk factors for serious infections in ANCA-associated vasculitis. Annals of the Rheumatic Diseases, Epub ahead of print. http://dx.doi.org/0.1136/ard-2022-223401, PMID: 36702528.

Sykes M, Chandran S, Kawai T, Levitsky J, Mapara M, Mathew J, Thomson A, Yamada K. (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107 (3), 564-569. http://dx.doi.org/10.1097/TP.0000000000004473, PMID: 36808845

Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC; Type 1 Diabetes TrialNet Study Group. (2023). Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. . Diabetes Care., Epub ahead of print. http://dx.doi.org/10.2337/dc22-2200, PMID: 36920087

Sever ML, Calatroni A, Roberts G, Du Toit G, Bahnson HT, Radulovic S, Larson D, Byron M, Santos AF, Huffaker MF, Wheatley LM, Lack G. (2023). Developing a Prediction Model for Determination of Peanut Allergy Status in the LEAP Studies. J Allergy Clin Immunol Pract, Epub ahead of print. http://dx.doi.org/10.1016/j.jaip.2023.04.032, PMID: 37146884

Logan K, Bahnson HT, Ylescupidez A, Beyer K, Bellach J, Campbell DE, Craven J, Du Toit G, Clare Mills EN, Perkin MR, Roberts G, van Ree R, Lack G (2023). Early introduction of peanut reduces peanut allergy across risk groups in pooled and causal inference analyses. Allergy, 78 (5), 1307-1318. http://dx.doi.org/10.1111/all.15597, PMID: 36435990

Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom G, Herold K AG019-T1D-101 Trial Investigators (2023). A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab. Diabetologia .. http://dx.doi.org/10.1007/s00125-023-06014-2, PMID: 37782353

Duan, M., Nguyen, D. C., Joyner, C. J., Saney, C. L., Tipton, C. M., Andrews, J., Lonial, S., Kim, C., Hentenaar, I., Kosters, A., Ghosn, E., Jackson, Knechtle, Maruthamuthu, Chandran, Martin, T., Rajalingam, R., Vincenti, F., Breeden, Sanz, Gibson, G., Lee, F. E. (2023). Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.. Cell Reports, 42 (7), 112682. http://dx.doi.org/10.1016/j.celrep.2023.112682, PMID: 37355988, PMCID: PMC10391632

Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley P. Cerosaletti (2023). Proinflammatory islet antigen reactive CD4 T cells are linked with response to alefacept in type 1 diabetes.. JCI Insight, Epub ahead of print. http://dx.doi.org/10.1172/jci.insight.167881, PMID: 37751304

Delgado AL, Preston-Hurlburt P, Lim N, Sumida TS, Long SA, McNamara J, Serti E, Higdon L, Herold KC (2023). Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes. medRxiv, Epub ahead of print. http://dx.doi.org/10.1101/2023.07.11.23292344, PMID: 37502867, PMCID: PMC10370230

Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD (2023). Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clinical Immunology, Epub ahead of print. http://dx.doi.org/10.1016/j.clim.2023.109829, PMID: 37907122

Jones SM, Nadeau KC, Nowak-Węgrzyn A, Wood RA, Sampson HA, Scurlock AM, Chinthrajah RS, Wang J, Pesek RD, Sindher SB, Kulis M, Spain K, Babineau DC, Chin H, Laurienzo-Panza J, Yan R, Qin T, Whitehouse D, Sever ML, Sanda S, Plaut M, Wheatley LM, Burks AW, Immune Tolerance Network (2022). Efficacy and safety of oral immunotherapy in children aged 1-3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study. Lancet, 399 (10322), 359-371. http://dx.doi.org/10.1016/S0140-6736(21)02390-4, PMID: 35065784, PMCID: PMC9119642

Kanchan K, Grinek S, Bahnson HT, Ruczinski I, Shankar G, Larson D, Du Toit G, Barnes KC, Sampson HA, Suarez-Farinas M, Lack G, Nepom GT, Cerosaletti K, Mathias RA (2022). HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy. J Clin Invest, 132 (1). http://dx.doi.org/10.1172/JCI152070, PMID: 34981778, PMCID: PMC8718139

Bajzik V, DeBerg HA, Garabatos N, Rust BJ, Obrien KK, Nguyen QA, O'Rourke C, Smith A, Walker AH, Quinn C, Gersuk VH, Farrington M, Jeong D, Vickery BP, Adelman DC, Wambre E (2022). Oral desensitization therapy for peanut allergy induces dynamic changes in peanut-specific immune responses. Allergy, Epub ahead of print. http://dx.doi.org/doi.org/10.1111/all.15276, PMID: 35266148

Marwaha AK, Chow S, Pesenacker AM, Cook L, Sun A, Long SA, Yang JHM, Ward-Hartstonge KA, Williams E, Domingo-Vila C, Halani K, Harris KM, Tree TIM, Levings MK, Elliott T, Tan R, Dutz JP (2022). A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes. Immunotherapy Advances, 2 (1), 1 -13. http://dx.doi.org/10.1093/immadv/ltab022, PMID: 35072168, PMCID: PMC8769169

Brough HA, Lanser BJ, Sindher SB, Teng JMC, Leung DYM, Venter C, Chan SM, Santos AF, Bahnson HT, Guttman-Yassky E, Gupta RS, Lack G, Ciaccio CE, Sampath V, Nadeau KC, Nagler CR. (2022). Early intervention and prevention of allergic diseases. Allergy, 77 (2), 416-441. http://dx.doi.org/10.1111/all.15006, PMID: 34255344

Monach PA, Warner RL, Lew R, Tomasson G, Specks U, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CGM, Langford CA, Seo P, St Clair EW, Spiera R, Johnson KJ, Merkel PA (2022). Serum Biomarkers of Disease Activity in Longitudinal Assessment of Patients with ANCA-Associated Vasculitis. ACR Open Rheumatology, 4 (2), 168-176. http://dx.doi.org/doi.org/10.1002/acr2.11366, PMID: 34792864, PMCID: PMC8843765

Shimozawa K, Contreras-Ruiz L, Sousa S, Zhang R, Bhatia U, Crisalli KC, Brennan LL, Turka LA, Markmann JF, Guinan EC. (2022). Ex vivo generation of regulatory T cells from liver transplant recipients using costimulation blockade. Am J Transplant, 22 (2), 504-518. http://dx.doi.org/10.1111/ajt.16842, PMID: 34528383, PMCID: PMC9078620

Wood-Trageser MA, Lesniak D, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ (2022). Next Generation Pathology Detection of T cell-Antigen Presenting Cell Immune Synapses in Human Liver Allografts. Hepatology, Online ahead of print.. http://dx.doi.org/10.1002/hep.32666, PMID: 35819312

Corren J, Larson D, Altman MC, Segnitz RM, Avila PC, Greenberger PA, Baroody F, Moss MH, Nelson H, Burbank AJ, Hernandez ML, Peden D, Saini S, Tilles S, Hussain I, Whitehouse D, Qin T, Villarreal M, Sever M, Wheatley LM, Nepom GT, Sanda S. (2022). Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: a randomized controlled trial. Journal of Allergy and Clinical Immunology. , PMID: 36223848

Tang, Q. Leung, J. Peng, Y. Sanchez-Fueyo, A. Lozano, JJ. Lam, A. Lee, K. Greenland, JR. Hellerstein, M. Fitch, M. Li, KW. Esensten, JH. Putnam, AL. Lares, A. Nguyen, V. Liu, W. Bridges, ND. Odim, J. Demetris, AJ. Levitsky, J. Taner, T. Feng, S. (2022). Selective decrease of donor-reactive Tregs after liver transplantation limits Treg therapy for promoting allograft tolerance in humans. Sci Transl Med, 14, Online ahead of print. http://dx.doi.org/10.1126/scitranslmed.abo2628, PMID: 36322627

Speake C, Habib T, Lambert K, Hundhausen C, Lord S, Dufort MJ, Skinner SO, Hu A, Kinsman M, Jones BE, Maerz MD, Tatum M, Hocking AM, Nepom GT, Greenbaum CJ, Buckner JH (2022). IL-6-targeted therapies directed to cytokine or receptor blockade drive distinct alterations in T cell function. JCI Insight, Epub ahead of print. http://dx.doi.org/10.1172/jci.insight.159436, PMID: 36282595

Perito ER, Persyn E, Bucuvalas J, Martinez M, Mohammad S, Squires JE, Demetris AJ, Feng S. (2022). Graft Fibrosis Over 10 to 15 Years in Pediatric Liver Transplant Recipients: Multicenter Study of Paired, Longitudinal Surveillance Biopsies. Liver Transplantation, Epub ahead of print. http://dx.doi.org/10.1002/lt.26409, PMID: 35029022

Hübscher SG, Feng S, Gouw ASH, Haga H, Kang HJ, Kelly DA, Komuta M, Lesniak A, Popp BA, Verkade HJ, Yu E, Demetris AJ. (2022). Standardizing the histological assessment of late posttransplantation biopsies from pediatric liver allograft recipients. Liver Transplantation, 28 (9), 1475-1489. http://dx.doi.org/10.1002/lt.26482, PMID: 35429359

Smeekens JM, Baloh C, Lim N, Larson D, Qin T, Wheatley L, Kim EH, Jones SM, Burks AW, Kulis MD. (2022). Peanut-Specific IgG4 and IgA in Saliva Are Modulated by Peanut Oral Immunotherapy. The Journal of Allergy and Clinical Immunology, Epub ahead of print. http://dx.doi.org/10.1016/j.jaip.2022.07.030, PMID: 35944894

Gamerith G, Mildner F, Merkel PA, Harris K, Cooney L, Lim N, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Fervenza FC, Monach P, Ytterberg SR, Geetha D, Amann A, Wolf D, Specks U, Stone JH, Kronbichler A. (2022). Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission. Ann Rheum Dis, Epub ahead of print. http://dx.doi.org/10.1136/ard-2022-222479, PMID: 35973802

Mexhitaj I, Lim N, Fernandez-Velasco JI, Zrzavy T, Harris KM, Muraro PA, Villar LM, Bar-Or A, Cooney LA. (2022). Stabilization of leukocytes from cerebrospinal fluid for central immunophenotypic evaluation in multicenter clinical trials. J Immunol Methods, Epub ahead of print. http://dx.doi.org/10.1016/j.jim.2022.113344, PMID: 36041516

Huffaker M, Kanchan K, Bahnson H, Ruczinski I, Shankar G, Leung D, Baloh, C Du Toit G, Lack GT, Nepom G, Mathias R (2022). Epidermal Differentiation Complex Genetic Variation in Atopic Dermatitis and Peanut Allergy. J Allergy Clin Immunol, Epub ahead of print. http://dx.doi.org/10.1016/j.jaci.2022.11.008, PMID: 36403663

Grinek S, Suprun M, Raghunathan R, Tomalin LE, Getts R, Bahnson T, Lack G, Sampson HA, Suarez-Farinas M. (2022). Epitope-Specific IgE at 1 Year of Age Can Predict Peanut Allergy Status at 5 Years. Int Arch Allergy Immunol., Epub ahead of print, 1-6. http://dx.doi.org/10.1159/000526364, PMID: 36502801

Moura MC, Thompson GE, Nelson DR, Fussner LA, Hummel AM, Jenne DE, Emerling D, Fervenza FC, Kallenberg CGM, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Stone JH, Robinson WH, Specks U (2022). Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3. Arthritis Rheumatol, Epub ahead of print. http://dx.doi.org/10.1002/art.42418, PMID: 36515151

McKinney EF, Cuthbertson I, Harris KM, Smilek D, Connor C, Manferrari G, Carr EJ, Zamvil SS, Smith KGC (2021). A CD8 + NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis. Nat Commun, 12 (1), 635. http://dx.doi.org/10.1038/s41467-020-20594-2, PMID: 33504809, PMCID: PMC7840761

Diggins KE, Serti E, Muir VS, Rosasco M, Lu T, Balmas E, Nepom GT, Linsley PS (2021). Exhausted-like CD8 T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects. JCI Insight, 6 (3), 142680. http://dx.doi.org/10.1172/jci.insight.142680, PMID: 33351781, PMCID: PMC7934874

Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane Ellen, Layhadi JA, Wurtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR (2021). Differential Induction of Allergen-specific IgA Responses following Timothy Grass Subcutaneous and Sublingual Immunotherapy. J Allergy Clin Immunol, S0091-6749 (21), 00552-2. http://dx.doi.org/10.1016/j.jaci.2021.03.030, PMID: 33819508

Suarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA. (2021). Evolution of epitope-specific IgE and IgG 4 antibodies in children enrolled in the LEAP trial. The Journal of Allergy and Clinical Immunology, S0091-6749 (21). http://dx.doi.org/10.1016/j.jaci.2021.01.030, PMID: 33592205, PMCID: PMC8480440 

Shaked O, Demetris J, Levitsky J, Feng S, Loza BL, Punch J, Reyes J, Klintmalm G, Jackson W, DesMarais M, Sayre P, Shaked A, Reddy KR (2021). Impact of Donor and Recipient Clinical Characteristics and Hepatic Histology on Steatosis/Fibrosis Following Liver Transplantation. Transplantation, Online ahead of print. http://dx.doi.org/10.1097/TP.0000000000003681, PMID: 33982909

Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, Du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GWK, Roberts G (2021). EAACI guideline: Preventing the development of food allergy in infants and young children. Pediatric Allergy and Immunology, Online ahead of print. http://dx.doi.org/DOI: 10.1111/pai.13496, PMID: 33710678

Tanimine N, Burrell BE, Deng K, Rickert C, Lee KM, Feeney N, Pardo J, LeGuern C, Markmann JF (2021). Detection of alloreactive T cells from cryopreserved human peripheral blood mononuclear cells. J Immunol Methods, 491 (112987). http://dx.doi.org/https://doi.org/10.1016/j.jim.2021.112987, PMID: 33556344

Sims EK, Bundy BN, Stier K, Serti E, Lim N, Long SA, Geyer SM, Moran A, Greenbaum CJ, Evans-Molina C, Herold KC; Type 1 Diabetes TrialNet Study Group. (2021). Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals. Sci Transl Med., 13 (583). http://dx.doi.org/https://doi.org/10.1126/scitranslmed.abc8980, PMID: 33658358, PMCID: PMC8610022

Harris KM, Smilek DE, Byron M, Lim N, Barry WT, McNamara J, Garcet S, Konrad RJ, Stengelin M, Bathala P, Korman NJ, Feldman SR, Boh EE, Barber K, Laumann AE, Helfrich YR, Krueger GG, Sofen H, Bissonnette R, Krueger JG (2021). Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial. JAMA Dermatol., 157 (11), 1306-1315. http://dx.doi.org/10.1001/jamadermatol.2021.3492, PMID: 34643650, PMCID: PMC8515260

Suarez-Farinas M, Suprun M, Kearney P, Getts R, Grishina G, Hayward C, Luta D, Porter A, Witmer M, Du Toit G, Lack G, Chinthrajah RS, Galli SJ, Nadeau K, Sampson H (2021). Accurate and reproducible diagnosis of peanut allergy using epitope mapping. Allergy, 76 (12), 3789-3797. http://dx.doi.org/10.1111/all.14905, PMID: 33991353, PMCID: PMC8607840  (available on 2022-12-01)

Berti A, Hillion S, Hummel AM, Son YM, Chriti N, Peikert T, Carmona EM, Abdulahad WH, Heeringa P, Harris KM, St Clair EW, Brunetta P, Fervenza F, Langford C, Kallenberg C, Merkel P, Monach PA, Seo P, Spiera RF, Stone JH, Grandi G, Sun J, Pers JO, Specks U, Cornec D (2021). Circulating autoreactive proteinase 3 + B cells and tolerance checkpoints in ANCA-associated vasculitis. JCI Insight, 6 (22), e150999. http://dx.doi.org/10.1172/jci.insight.150999, PMID: 34618687, PMCID: PMC8663783

Linsley PS, Barahmand-Pour-Whitman F, Balmas E, DeBerg HA, Flynn KJ, Hu AK, Rosasco M, Chen J, O'Rourke C, Serti E, Gersuk VH, Motwani K, Seay HR, Brusko TM, Kwok WW, Speake C, Greenbaum CJ, Nepom GT, Cerosaletti K (2021). Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes. JCI Insight, 6 (22), e151349. http://dx.doi.org/10.1172/jci.insight.151349, PMID: 34806648

Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Steven M. Willi, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S, ITN058AI EXTEND Study Team (2021). IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight, 6 (21), e150074. http://dx.doi.org/10.1172/jci.insight.150074, PMID: 34747368, PMCID:  PMC8663550

Obradovic A, Shen Y, Sykes M, Fu J. (2021). Integrated Analysis Toolset for Defining and Tracking Alloreactive T-cell Clones After Human Solid Organ and Hematopoietic Stem Cell Transplantation. Software Impacts, 10. http://dx.doi.org/10.1016/j.simpa.2021.100142, PMID: 35291378, PMCID: PMC8920412

Fu J, Khosravi-Maharlooei M, Sykes M (2021). High Throughput Human T Cell Receptor Sequencing: A New Window Into Repertoire Establishment and Alloreactivity. Front Immunol, 12. http://dx.doi.org/10.3389/fimmu.2021.777756, PMID: 34804070, PMCID: PMC8604183

Irizar H, Kanchan K, Mathias RA, Bunyavanich S. (2021). Advancing Food Allergy Through Omics Sciences. J Allergy Clin Immunol, 9 (1), 119-129. http://dx.doi.org/10.1016/j.jaip.2020.07.044, PMID: 32777389, PMCID: PMC7855623

Kanchan K, Clay S, Irizar H, Bunyavanich S, Mathias RA (2021). Current insights into the genetics of food allergy. J Allergy Clin Immunol, 147 (1), 15-28. http://dx.doi.org/10.1016%2Fj.jaci.2020.10.039, PMID: 33436162, PMCID: PMC8261836

Song S, Manook M, Kwun J, Jackson AM, Knechtle SJ, Kelsoe G. (2021). Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Front Immunol, 12 (705140). http://dx.doi.org/10.3389/fimmu.2021.705140, PMID: 34326847, PMCID: PMC8313870

Diggins KE, Serti E, Muir V, Rosasco M, Lu T, Balmas E, Nepom G, Long SA, Linsley P (2021). Exhausted CD8+ T Cells linked to Alefacept response in T1D have distinct trajectories differing by KIR phenotype. JCI Insight, e142680.. http://dx.doi.org/10.1172/jci.insight.142680, PMID: 33351781, PMCID: PMC7934874

Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D (2020). Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited. Clin Pharmacokinet., 59 (4), 519-530. http://dx.doi.org/10.1007/s40262-019-00826-5, PMID: 31586310

Wiedeman AE, Muir VS, Rosasco M, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James E, Linsley PS, Long SA (2020). Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression. J Clin Invest, 130 (1), 480-490. http://dx.doi.org/10.1172/JCI126595, PMID: 31815738, PMCID: PMC6934185

Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Chase Crawford J, Alfei F, Alli S, Pereira Ribeiro S, Castellaw AH, McGargill MA, Jin H, Boi SH, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly R, Zehn D, James E, Nepom GT, Youngblood B (2020). Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol, 21 (5), 578-587. http://dx.doi.org/10.1038/s41590-020-0633-5, PMID: 32231298, PMCID: PMC7183435

Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James E, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR (2020). Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen. J Allergy Clin Immunol, 145 (6), 1585-1597. http://dx.doi.org/10.1016/j.jaci.2020.02.024, PMID: 32169380, PMCID: PMC8958045

Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC (2020). Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2. J Allergy Clin Immunol, epub ahead of print. http://dx.doi.org/10.1016/j.jaci.2020.04.009, PMID: 32333915, PMCID: PMC7175851

Atisha-Fregoso Y, Malkiel S, Harris KM, Byron M, Ding L, Kanaparthi S, Barry WT, Gao W, Ryker K, Tosta P, Askanase AD, Boackle SA, Chatham WW, Kamen DL, Karp DR, Kirou KA, Lim SS, Marder B, McMahon M, Parikh SV, Pendergraft WF 3rd, Podoll AS, Saxena A, Wofsy D, Diamond B, Smilek DE, Aranow C, Dall'Era M (2020). CALIBRATE: A Phase 2 Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis. Arthritis Rheumatol., 73 (1), 121-131. http://dx.doi.org/10.1002/art.41466, PMID: 32755035, PMCID: PMC7839443

Wood-Trageser MA, Xu Q, Zeevi A, Randhawa P, Lesniak A, Demetris AJ (2020). Precision transplant pathology. Curr Opin Organ Transplant, 25 (4), 412-419. http://dx.doi.org/10.1097/MOT.0000000000000772, PMID: 32520786, PMCID: PMC7737245

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Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, Immune Tolerance Network T1DAL Study Team (2013). Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Diabetes Endocrinol, 1 (4), 284-94. http://dx.doi.org/10.1016/S2213-8587(13)70111-6, PMID: 24622414, PMCID: PMC3957186

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2013). Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis. Arthritis Rheum, 65 (9), 2441-9. http://dx.doi.org/10.1002/art.38044, PMID: 23754238, PMCID: PMC4949954

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Isse K, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G, Demetris AJ (2013). Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells. Hepatology, 57 (4), 1632-43. http://dx.doi.org/10.1002/hep.26131, PMID: 23150208, PMCID: PMC3612393

Nelson EK, Piehler B, Rauch A, Ramsay S, Holman D, Asare S, Asare A, Igra M (2013). Ancillary study management systems: a review of needs. BMC Med Inform Decis Mak, 13 (5), 1-17. http://dx.doi.org/10.1186/1472-6947-13-5, PMID: 23294514, PMCID: PMC3564696

Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK (2012). Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA, 307 (3), 283-93. http://dx.doi.org/10.1001/jama.2011.2014, PMID: 22253395

Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA (2012). Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis. PLoS One, 7 (1), e30197. http://dx.doi.org/10.1371/journal.pone.0030197, PMID: 22279570, PMCID: 3261176

Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group (2012). Randomized controlled trial of atorvastatin in clinically isolated syndrome. Neurology, 78 (15), 1171-8. http://dx.doi.org/10.1212/WNL.0b013e31824f7fdd, PMID: 22459680, PMCID: PMC3320055

Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network (2012). Rapamycin/IL-2 combination therapy in Type 1 Diabetes. Diabetes, 61 (9), 2340-8. , PMID: 22721971, PMCID: PMC3425404

Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA (2012). Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes. J Immunol Methods, 384 (1-2), 25-31. , PMID: 22759401

Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G (2012). Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol, 131 (1), 135-143. , PMID: 23174658

Finak G, Jiang W, Pardo J, Asare A, Gottardo R (2012). QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data. BMC Bioinformatics, Sep (13), 252. , PMID: 23020243, PMCID: 3499158

Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR (2012). Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy. Allergy, 62 (2), 217-26. http://dx.doi.org/10.1111/j.1398-9995.2011.02745.x, PMID: 22077562

Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ (2012). Donor-specific indirect pathway analysis reveals a B-cell-independent signature which reflects outcomes in kidney transplant recipients. Am J Transplant., 12 (3), 640-8. http://dx.doi.org/10.1111/j.1600-6143.2011.03869, PMID: 22151236, PMCID: PMC3374729

James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR (2011). Long term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies. J Allergy Clin Immunol, 127 (2), 509-16. http://dx.doi.org/10.1016/j.jaci.2010.12.1080, PMID: 21281875

Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB (2011). Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant, 11 (7), 1464-77. http://dx.doi.org/10.1111/j.1600-6143.2011.03572.x, PMID: 21668634, PMCID: PMC3128680

Radassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA (2011). Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis. J Immunol, 187 (2), 1039-46. http://dx.doi.org/10.4049/jimmunol.1001543, PMID: 21653833, PMCID: PMC3131477

Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH (2011). Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial. The Open Arthritis Journal, 4 (1), 1-18.

Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Gu YZ, Snyder RD, Merkel PA (2011). Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheum, 36 (12), 3988-97. http://dx.doi.org/10.1002/art.30615, PMID: 21953143, PMCID: PMC3227746

Strober S, Spitzer TR, Lowsky R, Sykes M (2011). Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction. Semin Immunol, 23 (4), 273-81. http://dx.doi.org/10.1016/j.smim.2011.05.001, PMID: 21705229, PMCID: PMC3201788

Sachs DH, Sykes M, Kawai T, Cosimi AB (2011). Immuno-intervention for the induction of transplantation tolerance through mixed chimerism. Semin Immunol, 23 (3), 165-73. http://dx.doi.org/10.1016/j.smim.2011.07.001, PMID: 21839648, PMCID: PMC3178004

Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, LoCascio SA, Morokata T, Dey BR, Tolkoff-Rubin NT, Preffer F, Bonnefoix T, Kattleman K, Spitzer TR, Sachs DH, Sykes M (2011). Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation. Am J Transplant, 11 (6), 1236-47. http://dx.doi.org/10.1111/j.1600-6143.2011.03566.x, PMID: 21645255, PMCID: PMC3140222

Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB (2011). Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease. Transplantation, 91 (6), 672-6. http://dx.doi.org/10.1097/TP.0b013e31820a3068, PMID: 21217460, PMCID: PMC3232059

Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Seyfert-Margolis V, Bourcier K, Asare A, Lumley T, Gentleman R, Brinkman RR (2010). Per-channel basis normalization methods for flow cytometry data. Cytometry A, 77 (2), 121-31. http://dx.doi.org/10.1002/cyto.a.20823, PMID: 19899135, PMCID: PMC3648208

Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL (2010). Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest, 120 (6), 1836-47. http://dx.doi.org/10.1172/JCI39933, PMID: 20501946, PMCID: PMC2877933

Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI (2010). Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest, 120 (6), 1848-61. http://dx.doi.org/10.1172/JCI39922, PMID: 20501943, PMCID: PMC2877932

Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P (2010). Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun, 34 (4), 408-15. http://dx.doi.org/10.1016/j.jaut.2009.10.005, PMID: 19931408, PMCID: PMC2860016

Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CG, St. Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U, RAVE-ITN Research Group (2010). Rituximab versus cyclophosphamide for ANCA-associated vasculitis. New Eng J Med, 363 (3), 221-32. http://dx.doi.org/10.1056/NEJMoa090990, PMID: 20647199, PMCID: PMC3137658

LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman Sl, Spitzer TR, Tolkoff-Rubin N, Cosimi BA, Sachs DH, Sykes M (2010). Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation, 90 (12), 1607-15. http://dx.doi.org/10.1097/TP.0b013e3181ffbaff, PMID: 21085064, PMCID: PMC3059844

Grant J, Bourcier K, Wallace S, Pan D, Conway A, Seyfert-Margolis V, Wallace PK (2009). Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients. Cytometry B Clin Cytom, 72 (2), 69-78. http://dx.doi.org/10.1002/cyto.b.20446, PMID: 18690669

Asare A, Gao Z, Carey VJ, Wang R, Seyfert-Margolis V (2009). Power enhancement via multivariate outlier testing with gene expression arrays. Bioinformatics, 25 (1), 48-53. http://dx.doi.org/10.1093/bioinformatics/btn591, PMID: 19015138, PMCID: PMC2638936

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Knechtle SJ, Pascual J, Bloom DD, Torrealba JR, Jankowska-Gan E, Burlingham WJ, Kwun J, Colvin RB, Seyfert-Margolis V, Bourcier K, Sollinger HW (2009). Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. Am J Transplant, 9 (5), 1087-98. http://dx.doi.org/10.1111/j.1600-6143.2009.02581.x, PMID: 19344431

Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA, ImmuneTolerance Network ITN007AI Study Group (2009). Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years. Clin Immunol, 132 (2), 166-73. http://dx.doi.org/10.1016/j.clim.2009.04.007, PMID: 19443276, PMCID: PMC2735402

Yu J, Steck AK, Babu S, Yu L, Miao D, McFann K, Hutton J, Eisenbarth GS, Klingensmith G (2009). Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes. J Clin Endocrinol Metab, 94 (2), 504-10. http://dx.doi.org/10.1210/jc.2007-2694, PMID: 19050058, PMCID: PMC2646512

Babaya N, Liu E, Miao D, Li M, Yu L, Eisenbarth GS (2009). Murine high specificity/sensitivity competitive europium insulin autoantibody assay. Diabetes Technol Ther, 11 (4), 227-33. http://dx.doi.org/10.1089/dia.2008.0072, PMID: 19344197, PMCID: PMC2903340

de Jager W, Bourcier K, Rijkers GT, Prakken BJ, Seyfert-Margolis V (2009). Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays. BMC Immunol, 28 (10), 52. http://dx.doi.org/10.1186/1471-2172-10-52, PMID: 19785746, PMCID: PMC2761376

Porcheray F, Wong W, Saidman Sl, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E (2009). B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant, 9 (9), 2126-35. http://dx.doi.org/10.1111/j.1600-6143.2009.02738.x, PMID: 19624570, PMCID: PMC2837587

Kawai, T, Cosimi AB, Spitzer TR, Tolkoff-Rubin, N, Suthanthiran M, Saidman Sl, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DSC, Hertl M, Goes NB, Wong W, Williams WW, Colvin RB, Sykes M, Sachs DH (2008). HLA-Mismatched renal transplantation without maintenance immunosuppression. N Engl J Med, 358 (4), 353-61. http://dx.doi.org/10.1056/NEJMoa071074, PMID: 18216355, PMCID: PMC2819046

Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CRG, Rusche JR, Khoury SJ (2008). CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial. Neurology, 71 (12), 917-24. http://dx.doi.org/10.1212/01.wnl.0000325915.00112.61, PMID: 18794494

Francis JN, James LK, Paraskevopoulos G, Wong C, Calderon MA, Durham SR, Till SJ (2008). Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity. J Allergy Clin Immunol, 121 (5), 1120-5. http://dx.doi.org/10.1016/j.jaci.2008.01.072, PMID: 18374405

Srikantha M, Sergeant R, Khan T, Lechler RI, Davey N, Hernandez-Fuentes MP, Warrens AN (2008). Retrospective tissue typeing of the kidney donor from recipient urine. Kidney Int, 74 (7), 952-5. http://dx.doi.org/10.1038/ki.2008.340, PMID: 18633344

O'Connor MJ, Shankar RD, Parrish DB, Das AK (2008). Knowledge-data integration for temporal reasoning in a clinical trial system. Int J Med Inform, 78 (1), S77-85. http://dx.doi.org/10.1016/j.ijmedinf.2008.07.013, PMID: 18789876

Lee JA, Spidlen J, Boyce K, Cai J, Crosbie N, Dalphin M, Furlong J, Gasparetto M, Goldberg M, Goralczyk EM, Hyun B, Jansen K, Kollmann T, Kong M, Leif R, McWeeney S, Moloshok TD, Moore W, Nolan G, Nolan J, Nikolich-Zugich J, Parrish D, Purcell B, Qian Y, Selvaraj B, Smith C, Tchuvatkina O, Wertheimer A, Wilkinson P, Wilson C, Wood J, Zigon R; International Society for Advancement of Cytometry Data Standards Task Force, Scheuermann RH, Brinkman RR (2008). MIFlowCyt: the minimum information about a Flow Cytometry Experiment. Cytometry, 73 (10), 926-30. http://dx.doi.org/10.1002/cyto.a.20623, PMID: 18752282, PMCID: PMC2773297

Asare AL, Kolchinsky SA, Gao Z, Wang R, Raddassi K, Bourcier K, Seyfert-Margolis V (2008). Differential gene expression profiles are dependent upon method of peripheral blood collection and RNA isolation. BMC Genomics, 10 (9), 474. http://dx.doi.org/10.1186/1471-2164-9-474, PMID: 18847473, PMCID: PMC2573897

Feng S (2008). Long-term management of immunosuppression after pediatric liver transplantation: is minimization or withdrawal desirable or possible or both?. Curr Opin Organ Transplant, 13 (5), 506-12. http://dx.doi.org/10.1097/MOT.0b013e328310b0f7, PMID: 19060534, PMCID: PMC2727645

Levesque MC, St Clair EW. (2008). B cell-directed therapies for autoimmune disease and correlates of disease response and relapse. J Allergy Clin Immunol, 121 (1), 13-21. http://dx.doi.org/10.1016/j.jaci.2007.11.030, PMID: 18206502

Xu Q, Lee J, Jankowska-Gan E, Schultz J, Roennburg DA, Haynes LD, Kusaka S, Sollinger HW, Knechtle SJ, Vanbuskirk AM, Torrealba JR, Burlingham WJ (2007). Human CD4+CD25low Adaptive T Regulatory Cells Suppress Delayed-Type Hypersensitivity during Transplant Tolerance. J Immunol, 178 (6), 3983-95. , PMID: 17339499

Derks RA, Jankowska-Gan E, Xu Q, Burlingham WJ (2007). Dendritic cell type determines the mechanism of bystander suppression by adaptive T regulatory cells specific for the minor antigen HA-1. J Immunol, 179 (6), 3443-51. , PMID: 17785778

Klunker S, Saggar LR, Seyfert-Margolis V, Asare AL, Casale TB, Durham SR, Francis JN, Immune Tolerance Network Group (2007). Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding. J Allergy Clin Immunol, 120 (3), 688-95. , PMID: 17631952

Baschal EE, Aly TA, Babu SR, Fernando MS, Yu L, Miao D, Barriga KJ, Norris JM, Noble JA, Erlich HA, Rewers MJ, Eisenbarth GS (2007). HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4DQB1*0302 DAISY population. Diabetes, 56 (9), 2405-2409. , PMID: 17513705

Liu E, Eisenbarth GS (2007). Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays. Clin Immunol, 125 (2), 120-126. , PMID: 17904423, PMCID: PMC2104491

Wang J, Miao D, Babu S, Yu J, Barker J, Klingensmith G, Rewers M, Eisenbarth GS, Yu L (2007). Prevelence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity. J Clin Endocrinol, 92 (1), 88-92. , PMID: 17062766

Yu L, Wang J, O'Dell JR, Oates J, Arend WP, Eisenbarth GS (2007). Anti-dsDNA antibody assay: high specificity and sensitivity with a filtration radioassay in comparison to low specificity with standard ELISA. J Rheumatol, 34 (4), 734-739. , PMID: 17407230

Zhang L, Barker JM, Babu S, Su M, Stenerson M, Cheng M, Shum A, Zamir E, Badolato R, Law A, Eisenbarth GS, Anderson MS (2007). A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1. Clin Immunol, 125 (2), 131-137. , PMID: 17825626, PMCID: PMC2080870

Kis J, Engelmann P, Farkas K, Richman G, Eck S, Lolley J, Jalahej H, Borowiec M, Kent SC, Treszl A, Orban T. (2007). Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus. J Leukoc Biol, 81 (3), 654-662. , PMID: 17151140

Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA, Rewers MJ, Eisenbarth GS, Fain PR (2006). Multi-SNP analysis of MHC region: Remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes, 55 (5), 1265-1269. , PMID: 16644681

Aly TA, Ide A, Jahromi MM, Barker JM, Fernando MS, Babu SR, Yu L, Miao D, Erlich HA, Fain PR, Barriga KJ, Norris JM, Rewers MJ, Eisenbarth GS (2006). Extreme genetic risk for type 1A diabetes. Proc Natl Acad Sci, 103 (38), 14074-14079. , PMID: 16966600, PMCID: PMC1563993

Casale TB, Busse WW, Kline JN, Ballas ZK, Moss MH, Townley RG, Mokhtarani M, Seyfert-Margolis V, Asare A, Bateman K, Deniz Y, Immune Tolerance Network (2006). Omalizumab pretreatment decreases acute reactions following rush immunotherapy for ragweed-induced seasonal allergic rhinitis. J Allergy Clin Immunol, 117 (1), 134-140. , PMID: 16387596

Creticos PS, Schroeder JT, Hamilton RG, Balcer-Whaley SL, Khattignavong AP, Lindblad R, Li H, Coffman R, Seyfert V, Eiden JJ, Broide D, Immune Tolerance Network Group (2006). Immunotherapy with a ragweed–toll-like receptor 9 agonist vaccine for allergic rhinitis. New Engl J Med, 355 (14), 1445-1455. , PMID: 17021320

Fudaba Y, Spitzer TR, Shaffer J, Kawai T, Fehr T, Delmonico F, Preffer F, Tolkoff-Rubin N, Dey BR, Saidman Sl, Kraus A, Bonnefoix T, McAfee S, Power K, Kattleman K, Colvin RB, Sachs DH, Cosimi AB, Sykes M (2006). Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses. Am J Transplant, 6 (9), 2121-2133. , PMID: 16796719

Seyfert-Margolis V, Gisler TD, Asare AL, Wang RS, Dosch HM, Brooks-Worrell B, Eisenbarth GS, Palmer JP, Greenbaum CJ, Gitelman SE, Nepom GT, Bluestone JA, Herold KC (2006). Analysis of T cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study. Diabetes, 55 (9), 2588-2594. , PMID: 16936208

Shamji MH, Wilcock LK, Wachholz PA, Dearman RJ, Kimber I, Wurtzen PA, Larché M, Durham SR, Francis JN (2006). The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses. J Immunol Meth, 317 (1-2), 71-79. , PMID: 17070537, PMCID: PMC1934503

Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, Polonsky KS, Reems JA, Bretzel RG, Bertuzzi F, Froud T, Kandaswamy R, Sutherland DE, Eisenbarth G, Segal M, Preiksaitis J, Korbutt GS, Barton FB, Viviano L, Seyfert-Margolis V, Bluestone J, Lakey JR (2006). International trial of the Edmonton protocol for islet transplantation. New Engl J Med, 355 (13), 1318-1330. , PMID: 17005949

Bourdette DN, Edmonds E, Smith C, Bowen JD, Guttmann CR, Nagy ZP, Simon J, Whitham R, Lovera J, Yadav V, Mass M, Spencer L, Culbertson N, Bartholomew RM, Theofan G, Milano J, Offner H, Vandenbark AA (2005). A highly immunogenic trivalent T cell receptor peptide vaccine. Multiple Sclerosis, 11 (5), 552-561. , PMID: 16193893

Bunde T, Kirchner A, Hoffmeister B, Habedank D, Hetzer R, Cherepnev G, Proesch S, Reinke P, Volk HD, Lehmkuhl H, Kern F (2005). Protection from cytomegalovirus after transplantation is correlated with immediate early 1–specific CD8 T cells. J Exp Med, 201 (7), 1031-1036. , PMID: 15795239, PMCID: PMC2213133

Danke NA, Koelle DM, Kwok WW (2005). Persistence of herpes simplex virus type 2 VP16-specific CD4(+) T cells. Hum Immunol, 66 (7), 777-787. , PMID: 16112025

Game DS, Hernandez-Fuentes MP, Lechler RI (2005). Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro. Am J Transplant, 5 (3), 454-464. , PMID: 15707399

Giannoni F, Barnett J, Bi K, Samodal R, Lanza P, Marchese P, Billetta R, Vita R, Klein MR, Prakken B, Kwok WW, Sercarz E, Altman A, Albani S (2005). Clustering of T cell ligands on artificial APC membranes influences T cell activation and protein kinase C theta translocation to the T cell plasma membrane. J Immunol, 174 (6), 3204-3211. , PMID: 15749850

Gonzalez JC, Kwok WW, Wald A, McClurkan CL, Huang J, Koelle DM (2005). Expression of cutaneous lymphocyte-associated antigen and E-selectin ligand by circulating human memory CD4+ T lymphocytes specific for herpes simplex virus type 2. J Infect Dis, 191 (2), 243-254. , PMID: 15609235, PMCID: PMC1255909

Huan J, Culbertson N, Spencer L, Bartholomew R, Burrows GG, Chou YK, Bourdette D, Ziegler SF, Offner H, Vandenbark AA (2005). Decreased Foxp3 levels in multiple sclerosis patients. J Neurosci Res, 81 (1), 45-52. , PMID: 15952173

Mallone R, Kochik SA, Reijonen H, Carson B, Ziegler SF, Kwok WW, Nepom GT (2005). Functional avidity directs T-cell fate in autoreactive CD4+ T-cells. Blood, 106 (8), 2798-2805. , PMID: 16030184, PMCID: PMC1895305

Muthukumar T, Dadhania D, Ding R, Snopkowski C, Nagvi R, Lee JB, Hartono C, Li B, Sharma VK, Seshan SV, Kapur S, Hancock WW, Schwartz JE, Suthanthiran M (2005). Messenger RNA for FOXP3 in the urine of renal allograft recipients. New Engl J Med, 353 (22), 2342-2351. , PMID: 16319383

Offner H, Vandenbark AA (2005). Congruent effects of estrogen and T cell receptor peptide therapy on regulatory T cells in EAE and MS. Intl Rev Immunol, 24 (5-6), 447-477. , PMID: 16318990

Vandenbark AA (2005). TCR peptide vaccination in multiple sclerosis: boosting a deficient natural regulatory network that may involve TCR-specific CD4. Curr Drug Targets Inflamm Allergy, 4 (2), 217-229. , PMID: 15853744

Barker JM, Barriga KJ, Yu L, Miao D, Erlich HA, Norris JM, Eisenbarth GS, Rewers M, Diabetes Autoimmunity Study in the Young (2004). Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab, 89 (8), 3896-3902. , PMID: 15292324

Barker JM, Goehrig SH, Barriga K, Hoffman M, Slover R, Eisenbarth GS, Norris JM, Klingensmith GJ, Rewers M, DAISY Study (2004). Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up. Diabetes Care, 27 (6), 1399-1404. , PMID: 15161795

Brennan DC, Shannon MB, Koch MJ, Polonsky KS, Desai N, Shapiro J (2004). Portal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation. Transplantation, 78 (1), 172-173. , PMID: 15257060

Danke NA, Koelle DM, Yee C, Beheray S, Kwok WW (2004). Autoreactive T cells in healthy individuals. J Immunol, 172 (10), 5967-5972. , PMID: 15128778

Mallone R, Kochik SA, Laughlin EM, Gersuk VH, Reijonen H, Kwok WW, Nepom GT (2004). Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells. Diabetes, 53 (4), 971-977. , PMID: 15047612

Maus MV, Kovacs B, Kwok WW, Nepom GT, Schlienger K, Riley JL, Allman D, Finkel TH, June CH (2004). Extensive replicative capacity of human central memory T cells. J Immunol, 172 (11), 6675-6683. , PMID: 15153483

Yang J, Jaramillo A, Shi R, Kwok WW, Mohanakumar T (2004). In vivo biotinylation of the major histo-compatibility complex (MHC) class II/peptide complex by co-expression of BirA enzyme for the generation of MHC class II/tetramers. Hum Immunol, 65 (7), 692-699. , PMID: 15301857

Ding R, Li B, Muthukumar T, Dadhania D, Medeiros M, Hartono C, Serur D, Seshan SV, Sharma VK, Kapur S, Suthanthiran M (2003). CD103 mRNA levels in urinary cells predict acute rejection of renal allografts. Transplantation, 5 (8), 1307-1312. , PMID: 12717221

Mazariegos GV, Zahorchak AF, Reyes J, Ostrowski L, Flynn B, Zeevi A, Thomson AW (2003). Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients. Am J Transplant, 3 (6), 689-696. , PMID: 12780560

Muthukumar T, Ding R, Dadhania D, Medeiros M, Li B, Sharma VK, Hartono C, Serur D, Seshan SV, Volk HD, Reinke P, Kapur S, Suthanthiran M (2003). Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation, 75 (9), 1565-1570. , PMID: 12792516

Reijonen H, Kwok WW (2003). Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes. Methods, 29 (3), 282-288. , PMID: 12725793

Miao D, Yu L, Tiberti C, Cuthbertson DD, Rewers M, di Mario U, Eisenbarth GS, Dotta F (2002). ICA512(IA-2) Epitope specific assays distinguish transient from diabetes associated autoantibodies. J Autoimmun, 18 (2), 191-196. , PMID: 11908951

Gebauer BS, Hricik DE, Atallah A, Bryan K, Riley J, Tary-Lehmann M, Greenspan NS, Dejelo C, Boehm BO, Hering BJ, Heeger PS (2002). Evolution of the Enzyme-Linked Immunosorbent Spot Assay for post-transplant alloreactivity as a potentially useful immune monitoring tool. Am J Transplant, 2 (9), 857-866. , PMID: 12392292

Ding R, Medeiros M, Dadhania D, Muthukumar T, Kracker D, Kong JM, Epstein SR, Sharma VK, Seshan SV, Li B, Suthanthiran M (2002). Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation, 74 (7), 987-994. , PMID: 12394843

Thomson AW, Mazariegos GV, Reyes J, Donnenberg VS, Donnenberg AD, Bentlejewski C, Zahorchak AF, O'Connell PJ, Fung JJ, Jankowska-Gan E, Burlingham WJ, Heeger PS, Zeevi A (2001). Monitoring the patient off immunosuppression: Conceptual framework for a proposed tolerance assay study in liver transplant recipients. Transplantation, 72 (8), S13-S22. , PMID: 11888150

Bluestone JA, Matthews JB, Krensky AM (2000). The Immune Tolerance Network: The "Holy Grail" comes to the clinic. J Am Soc Nephrol, 11 (11), 2141-2146. , PMID: 11053493

Review & Commentary

Baloh C, Mathias R (2023). Recent progress in the genetic and epigenetic underpinnings of atopy. Journal of Allergy and Clinical Immunology, 151 (1), 60-69. http://dx.doi.org/10.1016/j.jaci.2022.10.027, PMID: 36608983

Huffaker, M. F., Kanchan, K., Bahnson, H. T., Baloh, C., Lack, G., Nepom, G. T., & Mathias, R. A (2023). Incorporating genetics in identifying peanut allergy risk and tailoring allergen immunotherapy: A perspective on the genetic findings from the LEAP trial. Journal of Allergy and Clinical Immunology, Epub ahead of print. http://dx.doi.org/10.1016/j.jaci.2022.12.819, PMID: 36732171

Podestà MA, Sykes M. (2022). Chimerism-Based Tolerance to Kidney Allografts in Humans: Novel Insights and Future Perspectives. Front Immunol, 12 (791725). http://dx.doi.org/10.3389/fimmu.2021.791725, PMID: 35069574, PMCID: PMC8767096

Baloh CH, Huffaker MF and Laidlaw T. (2022). Biomarkers and mechanisms of tolerance induction in food allergic patients drive new therapeutic approaches. Front Immunol, 13. http://dx.doi.org/10.3389/fimmu.2022.972103, PMID: 36263023, PMCID: PMC9574092

Nepom, GT (2022). Synergistic targeting of immunologic pathways to empower durable tolerance therapies. Front Immunol, 13 (962177). http://dx.doi.org/10.3389/fimmu.2022.962177, PMID: 36119087, PMCID: PMC9478166

Santos, A. F., Evans, E., O'Rourke, C., Bahnson, H. T., Lack, G. (2022). Reply to: Life-threatening anaphylaxis to peanut — impossible to predict?. Journal of Allergy and Clinical Immunology, 149 (3), 1129-1131. http://dx.doi.org/10.1016/j.jaci.2021.12.766, PMID: 35000772

Huffaker M (2022). The Prevention of Milk Allergy and the Risks of Stopping Too Soon. J Allergy Clin Immunol Pract, 10 (1), 180-181. http://dx.doi.org/10.1016/j.jaip.2021.09.011, PMID: 35000732

Durham SR, Shamji MH. (2022). Allergen immunotherapy: past, present and future. Nat Rev Immunol, Epub ahead of print, 1-12. http://dx.doi.org/10.1038/s41577-022-00786-1, PMID: 36253555, PMCID: PMC9575636

Linsley PS, Greenbaum CJ, GT Nepom (2021). Uncovering Pathways to Personalized Therapies in Type 1 Diabetes. Diabetes, 7 (4), 831-841. http://dx.doi.org/10.2337/db20-1185, PMID: 33741606, PMCID: PMC7980192

Huffaker M F, Sanda S, Chung S, St. Clair EW, Nepom GT, Smilek DE (2021). Approaches to Establishing Tolerance in Immune Mediated Diseases. Front Immunol, 12, 744804. http://dx.doi.org/10.3389/fimmu.2021.744804

Krawiec M, Fisher HR, Du Toit G, Bahnson HT, Lack G. (2021). Overview of oral tolerance induction for prevention of food allergy—Where are we now?. Allergy, 76 (9), 2684-2698. http://dx.doi.org/10.1111/all.14758, PMID: 33539570

Renz H, Allen KJ, Sicherer SH, Sampson HA, Lack G, Beyer K, Oettgen HC (2018). Food allergy. Nat Rev Dis Primers, 4 (4), 17098. http://dx.doi.org/10.1038/nrdp.2017.98, PMID: 29300005

Newell KA, Turka LA, Adams AB (2018). Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.. Hum Immunol., 79 (5), 380-387. http://dx.doi.org/10.1016/j.humimm.2018.02.007, PMID: 29448053, PMCID: PMC5924709

Burks AW, Sampson HA, Plaut M, Lack G, Akdis C (2018). Treatment for food allergy. J Allergy Clin Immunol, 141 (1), 1-9. http://dx.doi.org/10.1016/j.jaci.2017.11.004, PMID: 29307409

Sampson HA, O'Mahony, L. Burks, AW. Plaut, M. Lack, Akdis CA (2018). Mechanisms of food allergy. J Allergy Clin Immunol, 141 (1), 11-19. http://dx.doi.org/10.1016/j.jaci.2017.11.005, PMID: 29307410

Sykes M (2018). Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol, 79 (5), 334-342. http://dx.doi.org/10.1016/j.humimm.2017.12.011, PMID: 29289741, PMCID: PMC5924718

Fisher HR, Du Toit G, Bahnson HT, Lack G (2018). The challenges of preventing food allergy: Lessons learned from LEAP and EAT. Ann Allergy Asthma Immunol, 121 (3), 313-319. http://dx.doi.org/10.1016/j.anai.2018.06.008, PMID: 29909054

Hemmings O, Kwok M, McKendry R, Santos AF (2018). Basophil Activation Test: Old and New Applications in Allergy. Current Allergy and Asthma Reports, 18 (77). http://dx.doi.org/10.1007/s11882-018-0831-5, PMID: 30430289

Wang J, Lack G (2017). Food Allergy: Unmet Needs and New Perspectives. J Allergy Clin Immunol Pract, 5 (2), 295. http://dx.doi.org/10.1016/j.jaip.2017.01.002, PMID: 28283155

Bahnson HT, Du Toit G, Lack G (2017). Statistical Considerations of Food Allergy Prevention Studies. J Allergy Clin Immunol Pract, 5 (2), 274-82. http://dx.doi.org/10.1016/j.jaip.2016.12.007, PMID: 28283152

Nepom GT, Ramsey BW, Lonial S (2017). Academic, Foundation, and Industry Collaboration in Finding New Therapies. N Engl J Med, 376 (18), 1762-9. http://dx.doi.org/10.1056/NEJMra1612575, PMID: 28467868

Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276 (1), 192-212. http://dx.doi.org/10.1111/imr.12523, PMID: 28258702, PMCID: PMC5338458

Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J (2017). Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'. Allergy, 72 (8), 1267-71. http://dx.doi.org/10.1111/all.13127, PMID: 28691223

Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol. http://dx.doi.org/10.1016/j.cellimm.2017.07.008, PMID: 28754194

Zuber J, Sykes M (2017). Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol., 38 (11), 829-43. http://dx.doi.org/10.1016/j.it.2017.07.008, PMID: 28826941, PMCID: PMC5669809

Ehlers MR (2016). Immune Interventions to Preserve β Cell Function in Type 1 Diabetes. J Investig Med, 64 (1), 7-13. http://dx.doi.org/10.1097/JIM.0000000000000227, PMID: 26225763, PMCID: PMC4732932

Ehlers MR (2016). Strategies for clinical trials in type 1 diabetes. J Autoimmun, Jul (71), 88-96. http://dx.doi.org/10.1016/j.jaut.2016.03.008, PMID: 27068279, PMCID: PMC4903883

Buckner JH, Nepom GT (2016). Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes. J Autoimmun, Jul (71), 44-50. http://dx.doi.org/10.1016/j.jaut.2016.02.009, PMID: 26948997, PMCID: PMC4903876

Asare AL, Carey VJ, Rotrosen D, Nepom GT (2016). Clinical trial data access: Opening doors with TrialShare. J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2016.05.034, PMID: 27474121

Du Toit G, Lack G, Tsakok T, Lack S (2016). Prevention of food allergy. J Allergy Clin Immunol, 137 (4), 998-1010. http://dx.doi.org/10.1016/j.jaci.2016.02.005, PMID: 27059727

Smilek DE; St Clair EW (2015). Solving the puzzle of autoimmunity: critical questions. F1000Prime Rep, 3 (7), 17. http://dx.doi.org/10.12703/P7-17, PMID: 25750735, PMCID: PMC4335798

McDonald-Hyman C, Turka LA, Blazar BR (2015). Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Sci Transl Med, 7 (280), 280rv2. http://dx.doi.org/10.1126/scitranslmed.aaa6853., PMID: 25810312, PMCID: PMC4425354

Kimberly RP (2015). The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67 (7), 1700-2. http://dx.doi.org/10.1002/art.39148, PMID: 25891203

Ehlers MR, Rigby MR (2015). Targeting Memory T Cells in Type 1 Diabetes. Curr Diab Rep, 15 (11), 84. http://dx.doi.org/10.1007/s11892-015-0659-5, PMID: 26370695

Newell KA, Turka LA (2015). Tolerance signatures in transplant recipients. Curr Opin Organ Transplant, 20 (4), 400-5. http://dx.doi.org/10.1097/MOT.0000000000000207, PMID: 26107969, PMCID: PMC4524570

Demetris AJ, Zeevi A, O'Leary JG (2015). ABO-compatible liver allograft antibody-mediated rejection: an update. Curr Opin Organ Transplant, 20 (3), 314-24. http://dx.doi.org/10.1097/MOT.0000000000000194, PMID: 25944231, PMCID: PMC4646419

Santos AF, Du Toit G, Lack G (2015). Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?. J Allergy Clin Immunol Pract, 3 (3), 429-30. http://dx.doi.org/10.1016/j.jaip.2014.12.009, PMID: 25956314

Wofsy D, Diamond B, Houssiau FA (2015). Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America. Arthritis Rheumatol, 67 (5), 1144-6. http://dx.doi.org/10.1002/art.39067, PMID: 25779381, PMCID: PMC4523131

Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ (2014). Tolerance: one transplant for life. Transplantation, 98 (2), 117-121. http://dx.doi.org/10.1097/TP.0000000000000260, PMID: 24926829, PMCID: PMC4101034

Sykes M (2014). Transplantation: moving to the next level. Immunol Rev, 258 (1), 5-11. http://dx.doi.org/10.1111/imr.12161, PMID: 24517422, PMCID: PMC4038030

Ehlers MR (2014). Immune-modulating effects of alpha-1 antitrypsin. Biol Chem., 395 (10), 1187-93. http://dx.doi.org/10.1515/hsz-2014-0161, PMID: 24854541, PMCID: PMC4237306

Rigby MR, Ehlers MR (2014). Targeted immune interventions for type 1 diabetes: not as easy as it looks!. Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8. http://dx.doi.org/10.1097/MED.0000000000000075, PMID: 24983393, PMCID: PMC4133939

Smilek DE, Ehlers MR, Nepom GT (2014). Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis Model Mech, 7 (5), 503-13. http://dx.doi.org/10.1242/dmm.015099, PMID: 24795433, PMCID: PMC4007402

Nepom GT, Ehlers M, Mandrup-Poulsen T (2013). Anti-cytokine therapies in T1D: Concepts and strategies. Clin Immunol, 14 (3), 279-285. http://dx.doi.org/10.1016/j.clim.2013.02.003, PMID: 23510726, PMCID: 3700624

Kawai T, Sachs DH (2013). Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant, 18 (4), 402-407. http://dx.doi.org/10.1097/MOT.0b013e328363621d, PMID: 23838644

Demetris AJ, Isse K (2013). Tissue biopsy monitoring of operational tolerance in liver allograft recipients. Curr Opin Organ Transplant, 18 (3), 345-353. http://dx.doi.org/10.1097/MOT.0b013e3283615d48, PMID: 23619515

Tang Q, Bluestone JA (2013). Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med, 3 (11), na. http://dx.doi.org/10.1101/cshperspect.a015552, PMID: 24186492

Zarin D (2013). Participant-level data and the new frontier in trial transparency. N Engl J Med, 369 (5), 468-469. http://dx.doi.org/10.1056/NEJMe1307268, PMID: 23902488

Sosinowski T, Eisenbarth GS (2013). Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res, 55 (1-3), 270-6. http://dx.doi.org/10.1007/s12026-012-8367-6, PMID: 22956469, PMCID: PMC3936464

Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P (2013). Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. J Allergy Clin Immunol., 132 (4), 991-3. http://dx.doi.org/10.1016/j.jaci.2013.04.049, PMID: 23768574

Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network (2013). HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med., 368 (19), 1850-2. http://dx.doi.org/10.1056/NEJMc1213779, PMID: 23656665, PMCID: PMC3760499

Tchao NK, Turka LA (2012). Lymphodepletion and homeostatic proliferation: Implications for transplantation. Am J Transplant, 12 (5), 1079-1090. http://dx.doi.org/10.1111/j.1600-6143.2012.04008.x, PMID: 22420320

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Pietropaolo M, Towns R, Eisenbarth GS (2012). Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes. Cold Spring Harb Perspect Med, 2 (10), na. http://dx.doi.org/10.1101/cshperspect.a012831, PMID: 23028135, PMCID: PMC3475400

Eisenbarth GS (2012). Prevention of type 1A diabetes mellitus. Endocr Pract, 18 (5), 745-749. http://dx.doi.org/10.4158/EP12080.OR, PMID: 22548954

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Nepom GT, St. Clair EW, Turka LA (2011). Challenges in the pursuit of immune tolerance. Immunol Rev, 241 (1), 49-62. http://dx.doi.org/10.1111/j.1600-065X.2011.01003.x, PMID: 21488889, PMCID: 3092524

Newell KA, Phippard D, Turka LA (2011). Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol, 23 (5), 655-659. http://dx.doi.org/10.1016/j.coi.2011.07.008, PMID: 21982510

Kawai T, Cosimi, Sachs DH (2011). Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant, 16 (4), 366-371. http://dx.doi.org/10.1097/MOT.0b013e3283484b2c, PMID: 21666482, PMCID: 3151013

Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB (2010). Ten years of the Immune Tolerance Network: an integrated clinical research organization. Sci Transl Med, 2 (19), 1-4. http://dx.doi.org/10.1126/scitranslmed.3000672, PMID: 20371484

Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group (2010). Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol, 160 (2), 176-184. , PMID: 20629979, PMCID: 2857940

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Isse K, Grama K, Abbott IM, Lesniak A, Lunz J, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJG (2010). Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis. Clin Liver Dis, 14 (4), 669-685. http://dx.doi.org/10.1016/j.cld.2010.07.004, PMID: 21055689

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St. Clair EW, Turka LA, Saxon A, Matthews JB, Sayegh MH, Eisenbarth GS, Bluestone J (2007). New reagents on the horizon for immune tolerance. Ann Rev Med, 58 (0), 329–46. , PMID: 16987079

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